priors.science/reviews/creatine

Creatine

The current evidence on 12 claims, ordered from most established to most contested. Each score is the panel’s evidence certainty — how firmly the literature supports the claim as stated.

12claims tracked
107primary papers reviewed
5 Jul 2026latest evidence review
Weeklyre-scored against new papers
1 Established · 4 Likely · 5 Uncertain · 1 Doubtful · 1 Refuted  |  four-reviewer panel · PICO Framework
SignalClaimStandingEvidence certaintyCorpus
StableCreatine increases strengthStrengthEstablished87%10
StableCreatine increases lean massMassLikely80%10
StableCreatine aids high-intensity workStrengthLikely70%10
StableCreatine in older adultsAgeingLikely68%10
StableEarly weight gain is waterMassLikely66%10
StableCreatine and depressionClinicalUncertain53%10
StableCreatine and sleep deprivationCognitionUncertain51%10
StableCreatine and cognitionCognitionUncertain48%10
StableCreatine in muscular dystrophyClinicalUncertain45%10
StableCreatine and bone healthAgeingUncertain43%10
StableNo cramping or dehydrationSafetyDoubtful24%10
StableNo kidney harm in healthy adultsSafetyRefuted14%10
Standing — what the evidence certainty means
Established≥ 85%Strong, consistent evidence. Unlikely to change.
Likely65–84%Well supported, with some gaps or indirect evidence.
Uncertain40–64%Mixed or limited evidence. Genuinely open.
Doubtful15–39%Little support; the weight of evidence leans against it.
Refuted< 15%The evidence contradicts it — confidently false as stated.
Recent signal
strengthenedNew evidence raised the certainty since the last review.
weakenedNew evidence lowered the certainty since the last review.
newA claim added to the review recently.
StableNo recent change to the standing.
Standing, evidence certainty and corpus are always shown. The study behind each move, why it moved, and the sceptic’s challenge are delivered to subscribers.
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