priors.science/reviews/intermittent-fasting-time-restricted-eating

Intermittent Fasting and Time Restricted Eating

The current evidence on 10 claims, ordered from most established to most contested. Each score is the panel’s evidence certainty: how firmly the literature supports the claim as stated.

10claims tracked
89primary papers reviewed
23 Oct 2026latest evidence review
0 Established · 4 Likely · 3 Uncertain · 3 Doubtful  |  four-reviewer panel · PICO Framework
ClaimStandingEvidence certaintyCorpus
Intermittent fasting lowers HbA1c in type 2 diabetesGLYLikely82%14
Time-restricted eating not superior to calorie restrictionWLLikely80%14
Time-restricted eating feasible with no serious adverse eventsSafLong-standingLikely78%15
Time-restricted eating reduces weight vs unrestricted eatingWLLikely78%14
Time-restricted eating reduces visceral and total fatWLUncertain64%16
Early time-restricted eating lowers blood pressureCMUncertain62%19
Time-restricted eating reduces lean muscle massWLUncertain60%16
Early time-restricted eating improves insulin sensitivity without weight lossGLYDoubtful45%15
Time-restricted eating cuts weight independent of caloriesGLYDoubtful33%16
Time-restricted eating improves blood lipid profileCMDoubtful30%18
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These claims are re-checked against new research as it is published. Track this topic for the full review, including each claim’s challenge and the papers behind it.
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Standing: what the evidence certainty means
Established≥ 85%Strong, consistent evidence. Unlikely to change.
Likely70–84%Well supported, with some gaps or indirect evidence.
Uncertain50–69%Mixed or limited evidence. Genuinely open.
Doubtful30–49%Little support; the weight of evidence leans against it.
Refuted< 30%The evidence contradicts it. Confidently false as stated.
A standing changes only when the score moves past a boundary by more than 4 points, the re-scoring noise floor; a score within 4 points of a boundary keeps its previous standing.
Where the evidence sits in time
Long-standingMost of this evidence is older than the rest of this field.