priors.science/reviews/vitamin-d

Vitamin D

The current evidence on 14 claims, ordered from most established to most contested. Each score is the panel’s evidence certainty: how firmly the literature supports the claim as stated.

16claims tracked
14assessed
222primary papers reviewed
26 Oct 2026latest evidence review
0 Established · 0 Likely · 4 Uncertain · 6 Doubtful · 4 Refuted  |  four-reviewer panel · PICO Framework
ClaimStandingEvidence certaintyCorpus
Pre-eclampsiaPregnancyUncertain64%19
High-dose vitamin D and fallsFallsUncertain60%20
Cancer mortalityCancerUncertain55%24
Type 2 diabetes preventionCardiometabolicUncertain50%22
Acute respiratory infectionRespiratoryDoubtful45%21
COVID-19 outcomesRespiratoryDoubtful37%20
Asthma exacerbationsRespiratoryDoubtful35%20
Cancer incidenceCancerDoubtful32%22
Major cardiovascular eventsCardiometabolicDoubtful32%22
Mortality in deficient adultsMortalityDoubtful30%20
Bone mineral density in adultsBoneRefuted27%24
All-cause mortalityMortalityRefuted27%24
Falls in older adultsFallsRefuted22%21
Fracture risk in general adultsBoneRefuted12%20
Track Vitamin D.
These claims are re-checked against new research as it is published. Track this topic for the full review, including each claim’s challenge and the papers behind it.
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Standing: what the evidence certainty means
Established≥ 85%Strong, consistent evidence. Unlikely to change.
Likely70–84%Well supported, with some gaps or indirect evidence.
Uncertain50–69%Mixed or limited evidence. Genuinely open.
Doubtful30–49%Little support; the weight of evidence leans against it.
Refuted< 30%The evidence contradicts it. Confidently false as stated.
A standing changes only when the score moves past a boundary by more than 4 points, the re-scoring noise floor; a score within 4 points of a boundary keeps its previous standing.